User:Saraswathi/Sandbox



SLIDING FILAMENT THEORY

SLIDING FILAMENT THEORY breifly  explains about the muscular contraction this is also called as the ratchet theory. And in this theory how actin filaments slide over the myosin filaments and form the actinomyosin complex. when the impulse passes to the neuron and reaches the neuromuscular junction releases the acteylcholine so the end plate potential causes the generation of the action potential in the muscle fibre. This action action potential spreads over the sarcolemma and also into the muscle fibre that causes muscle contraction. During contraction each cross bridge from the myosin filaments has three components namely hinge, arm and head. After binding with the active site of F actin, the myosin head starts going backwards with the arm so that the actin filament to move slowly. This way of titling is called as power stroke. After titling the head immediately breaks the contact with the actin filament and return to the normal position. Again when the work is done same process repeats number of times in order to release the energy of the work. During contraction of the muscles these filaments crossing over is actually results in the energy production. Formation of actinmyosin complex results in the contraction of muscles.